Familial Hypercholesterolemia (FH) is a hereditary dyslipidemia characterized by isolated and permanent elevated levels of circulating low-density lipoprotein (c-LDL).
An individual affected by FH has a 50% probability of having children developing FH.
Its prevalence is estimated at 1/300 to 1/500 in general population.
Familial Hypercholesterolemia is a worldwide healthcare issue*:
*Fernando Civeira. International Panel on Management of Familial Hypercholesterolemia. Guidelines for the diagnosis and management of heterozygous Familial Hypercholesteroleima. Atherosclerosis 173 (2004) 55-68.